Blood Viscosity and Cerebral Blood Flow Walzl and coworkers reported an improvement of neurological function following heparin-induced extracorporeal low-density lipoprotein precipitation (HELP) in a mixed group of acute stroke
نویسندگان
چکیده
1. Davis SM, Chua MG, Lichtenstein M, Rossiter SC, Binns D, Hopper JL. Cerebral hypoperfusion in stroke prognosis and brain recovery. Stroke. 1993;24:1691-1696. 2. Alexandrov AV, Ehrlich LE, Bladin CF, Norris JW. Cerebral perfusion index: a new marker for clinical outcome in acute stroke. J Neuroimaging. 1993;3:209-215. 3. Alexandrov AV, Bladin CF, Ehrlich LE, Norris JW. Cerebral perfusion index. Ann Neurol. 1993;34:289. Abstract. 4. Davis SM, Chua MG, Lichtenstein M, Rossiter SC, Tress BM, Hopper JL. Perfusion changes with recovery after stroke. Aust N Z J Med. 1993;23:568. Abstract. 5. Hanson SK, Grotta JC, Rhoades H, Tran HD, Lamki LM, Barron BJ, Taylor WJ. Value of single-photon emission-computed tomography in acute stroke therapeutic trials. Stroke. 1993;24: 1322-1329. 6. Davis SM. Transcranial Doppler ultrasonography and cerebral blood flow. In: Babikian VL, Wechsler LR, eds. Transcranial Doppler Ultrasonography. St Louis, Mo: CV Mosby Co; 1993;6:69-79. 7. Karnik R, Stelzer P, Slany J. Transcranial Doppler sonography monitoring of local intra-arterial thrombolysis in acute occlusion of the middle cerebral artery. Stroke. 1992;23:284-287.
منابع مشابه
Improved neurological recovery of cerebral infarctions after plasmapheretic reduction of lipids and fibrinogen.
BACKGROUND AND PURPOSE High fibrinogen levels have been assessed in cerebrovascular disease with a direct relation to both plasma and whole-blood viscosity, as well as cerebral blood flow. Heparin-induced extracorporeal low density lipoprotein precipitation (HELP) is a new method that safely and effectively reduces fibrinogen and plasma lipoproteins and improves blood flow properties. METHODS...
متن کاملHeparin-mediated extracorporeal LDL/fibrinogen precipitation--H.E.L.P.--in coronary and cerebral ischemia.
Cerebral and myocardial infarctions share common aspects of pathobiochemistry. The central problem is the oxygen supply of the infarcted region. To maintain this supply, H.E.L.P.-apheresis (Heparin-mediated Extracorporeal LDL/Fibrinogen Precipitation) has already proven beneficial in the prevention and therapy of myocardial infarction. Since H.E.L.P.-apheresis can lower significantly plasma vis...
متن کاملContribution of Nitric Oxide Synthase (NOS) Activity in Blood-Brain Barrier Disruption and Edema after Acute Ischemia/ Reperfusion in Aortic Coarctation-Induced Hypertensive Rats
Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...
متن کاملAssociation of abdominal aortic aneurysm and carotid artery stenosis.
1527 and in our study hypothermia clearly delayed increased intracra-nial pressure and thereby prolonged a higher cerebral perfusion pressure (/ > =.O1). We propose that even in a well-controlled experimental study, and despite prolonged postinsult control of extracerebral variables , 2 with an adequately severe cerebral focal ischemic insult small animal-to-animal variations will lead to the i...
متن کاملIncreased cerebral CO(2) reactivity after heparin-mediated extracorporal LDL precipitation (HELP) in patients with coronary heart disease and hyperlipidemia.
BACKGROUND AND PURPOSE There is experimental and clinical evidence that hypercholesterolemia leads to an impairment of endothelial function in coronary and cerebral arteries. Using transcranial Doppler sonography, we examined CO(2) reactivity as a marker of cerebral vasoreactivity in patients with coronary heart disease and hyperlipidemia before and after drastic lowering of LDL cholesterol, li...
متن کامل